王炜，副教授，硕士生导师。2007年毕业于北京大学化学与分子工程学院，同年进入美国俄亥俄州立大学攻读博士学位。2014年加入耶鲁大学分子生物物理与生物化学系Yong Xiong教授课题组进行博士后研究。2019年加入重庆医科大学生命科学研究院。

王炜副教授围绕“病原微生物与宿主之间的互作机制”这一关键科学问题，运用包括结构生物学、生物化学和细胞生物学在内的多种手段开展创新性研究，为开发抗感染新方法提供理论依据。主持国家自然科学基金、重庆市科委、重庆市教委及渝中区科委等多项科研课题。发表SCI论文15篇。作为第一作者/通讯作者（含共同）在Nature Communications，PNAS，Structure，Nucleic Acids Research等期刊发表论文5篇。获得重庆市高层次人才（第四类），任重庆市医学会呼吸病学专业委员会感染学组委员。申报中国发明专利3项。担任Genes and Diseases等高水平期刊审稿专家。

联系方式：wangwei@cqmu.edu.cn

主要研究方向：

1、病原微生物与宿主之间的互作机制

2、病原非编码RNA的结构和功能

代表性论著（^#第一作者，^*通讯作者）：

1. Haofeng Wang^#, Yunjie Xiao^#, Xia Chen^#, Mengwen Zhang, Guangxin Sun, Feng Wang, Lin Wang, Hanxiao Zhang, Xiaoyu Zhang, Xin Yang, Wenling Li, Yi Wei, Deqiang Yao, Bing Zhang, Jun Li, Wen Cui, Fenghua Wang, Cheng Chen, Wei Shen, Dan Su, Fang Bai, Jinhai Huang, Sheng Ye, Lei Zhang, Xiaoyun Ji,Wei Wang^*, Zefang Wang^*, Mark Hochstrasser^*, Haitao Yang^*. Crystal Structures of Wolbachia CidA and CidB Reveal Determinants of Bacteria-induced Cytoplasmic Incompatibility and Rescue.Nature Communications,2022, 13:1608

2. Yunjie Xiao^#, Hongli Chen^#, Haofeng Wang^#, Mengwen Zhang^#, Xia Chen, Jason M Berk, Lilin Zhang, Yi Wei, Wenling Li, Wen Cui, Fenghua Wang, Qianfan Wang, Can Cui, Ting Li, Cheng Chen, Sheng Ye, Lei Zhang, Xiaoyun Ji, Jinhai Huang,Wei Wang^*, Zefang Wang^*.Mark Hochstrasser^*, Haitao Yang^*.Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors.PNAS, 2021, 118(41):e2107699118.

3. Wen Cui^#, Elisabeth Braun^#,Wei Wang^#, Jinhong Tang^#, Yanyan Zheng^#, Benjamin Slater, Na Li, Cheng Chen, Qingxiang Liu, Bin Wang, Xiu Li, Yinkai Duan, Yunjie Xiao, Ruijiao Ti, Dominik Hotter, Xiaoyun Ji, Lei Zhang, Jun Cui, Yong Xiong, Daniel Sauter^*, Zefang Wang^*, Frank Kirchhoff^*, Haitao Yang^*. Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.PNAS, 2021, 118(15):e2022269118.

4.Wei Wang^#, Xinguo Chen, Sandra L Wolin^*, Yong Xiong^*.Structural basis for tRNA mimicry by a bacterial YRNA,Structure. 2018, 26(12): 1635-1644

5.Wei Wang^#, Nada Naiyer, Mithun Mitra, Jialin Li, Mark C Williams, Ioulia Rouzina, Robert J Gorelick, Zhengrong Wu, Karin Musier-Forsyth^*. Distinct nucleic acid interaction properties of HIV-1 nucleocapsid protein precursor NCp15 explain reduced viral infectivity,Nucleic Acids Research, 2014, 42(11): 7145-7159