王健宇，副研究员，博士生导师，重庆医科大学优秀青年学者。东北农业大学本硕博连读。主持国家自然科学基金面上项目/青年项目、重庆市自然科学基金面上项目、重庆市教委项目等。近五年以第一或通讯作者（含共同）先后在Pharmacological Research、Ebiomedicine、Protein&cell等杂志发表SCI论文23篇，总计影响因子141.41，其中大于10分的3篇，7-10分的6篇，5-6分12篇。

联系方式

102758@cqmu.edu.cn

招生方向

1.临床检验诊断学

2.生物化学与分子生物学

主要研究方向：

1.肿瘤干细胞在肿瘤发生发展和复发转移的分子机制研究

2.肿瘤分泌蛋白和微囊泡对肿瘤转移的分子机制研究

3.长非编码RNA在肿瘤发生发展过程中的作用机制

代表性论著（#第一作者，*通讯作者）

1.Bin Zeng^#, Yuting Chen^#, Hao Chen^#, Qiting Zhao, Zhiwei Sun, Doudou Liu, XiaoShuang Li, Yuhan Zhang,Jianyu Wang*, H. Rosie Xing*. Exosomal miR-211-5p regulates glucose metabolism, pyroptosis, and immune microenvironment of melanoma through GNA15.Pharmacological Research.2023 Feb;188:106660.

2.Zhiwei Sun^#, Doudou Liu^#, Bin Zeng, Qiting Zhao, Xiaoshuang Li, Hao Chen,Jianyu Wang*, H Rosie Xing*. Sec23a inhibits the self-renewal of melanoma cancer stem cells via inactivation of ER-phagy.Cell Commun Signal.2022 Mar 2;20(1):22.

3.Bin Zeng, Zhiwei Sun, Qiting Zhao, Doudou Liu, Hao Chen, Xiaoshuang Li, H Rosie Xing*,Jianyu Wang*.SEC23A Inhibit Melanoma Metastatic through Secretory PF4 Cooperation with SPARC to Inhibit MAPK Signaling Pathway.International Journal of Biological Sciences.2021 Jul 13;17(12):3000-3012.

4.Jianyu Wang*, Doudou Liu, Zhiwei Sun, Ting Ye, Jingyuan Li, Bin Zeng, Qiting Zhao, H Rosie Xing*. Autophagy augments the self-renewal of lung cancer stem cells by the degradation of ubiquitinated p53.Cell Death Dis.2021 Jan 19;12(1):98.

5.Zhiwei Sun, Shixia Zhou, Junling Tang, Ting Ye, Jingyuan Li, Doudou Liu, Jian Zhou*,Jianyu Wang*, H. Rosie Xing*. Sec23a mediates miR-200c augmented oligometastatic to polymetastatic progression.Ebiomedicine.2018; 37: 47–55.